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Two recent studies in older adults, one short-term (7 days) and one long-term (6 months), clearly showed the power of creatine to enhance muscle gain and fat loss, and improve several measures of functional performance including activities of daily living. These studies in humans are also supported by animal work. Using an animal model of aging, it was shown that creatine supplementation extended maximum life span by 3.5%. Even more impressive was the effect of creatine supplementation on "healthy" life span (defined as the age before animals were classified as suffering from disease) which significantly increased by 9%.

Bender A, Beckers J, Schneider I, H"lter SM, Haack T, Ruthsatz T, Vogt-Weisenhorn DM, Becker L, Genius J, Rujescu D, Irmler M, Mijalski T, Mader M, Quintanilla-Martinez L, Fuchs H, Gailus-Durner V, de Angelis MH, Wurst W, Schmidt J, Klopstock T. Creatine improves health and survival of mice. Neurobiol Aging. 2007 Apr 6; [Epub ahead of print]