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Posted in: Articles by ProSource, Supplement Articles
By Harry Fessel, ProSource Website Editor / Senior Writer | Jan 29, 2014



Advanced New FolliGenex Helps Promote Hair
Health and Provides Support of Male Function



It's one of the great ironies of the bodybuilding life. Testosterone is the wellspring from which many positive outcomes for men (muscle growth, libido, youthful vitality) originate. Most athletes make an effort to support optimized production of testosterone for exactly this reason.

Testosterone also occupies a position at the beginning of a chain of events that culminates in male pattern baldness. Though testosterone itself does not cause hair loss, male pattern baldness is kick-started by the transformation of testosterone into dihydrotestosterone (DHT). Testosterone converts into DHT due to the action of an enzyme called 5-alpha reductase. Hair follicles are especially sensitive to DHT, and actually miniaturize in its presence, resulting in a shorter hair lifespan and/or abnormal production of hair. Your hair thins and eventually the follicle goes dormant.

Think for a moment about the typical bunch of guys taking up permanent residence in the free-weights area of your gym, the haven for serious bodybuilders. What do you notice? These guys are big, right? They exude a macho aura. There's a lot of testosterone in the room. These guys are also more likely to be afflicted with receding hairlines, "widow's peaks," or maybe they just have a little ring of thin hair around the sides and backs of their heads. A lot of guys compensate for this hair loss by shaving their heads entirely. (Think of any lineup of competitors on the stage at Olympia Weekend.)

Now, there's nothing terribly wrong with pattern baldness. A guy like The Rock, Dwayne Johnson, can carry off that look. But many people can't. For most people, male pattern baldness just makes you look older than you are.

But wait. The story gets worse.

Hair Loss Pharmaceutical Drugs and Their
Negative Effect on Libido and Erectile Function

Turn on the TV to a sporting event or any program of interest to men and you'll be besieged with commercials touting "miracle drugs" that will "restore your hair." It's a big, big business. These pharmaceutical drugs (which are quite expensive and must be prescribed by your doctor) do in fact work for many people to slow the rate of hair loss, but unfortunately they only work for as long as you take them; when you stop, your hair loss begins again, often in as little as a few months.

Worse yet, they have also been associated with a number of undesirable side effects, including a disturbing decrease in libido and erectile capacity. And those decreases in libido and erectile capacity can linger even after you stop taking the drugs. A new study1 conducted at The George Washington University School of Medicine and Health Sciences, that will be published in the Journal of Sexual Medicine, suggests men who take the drug finasteride, the active ingredient in a number of prescribed hair-loss pharmaceutical drugs, may report an on-going reduction in sex drive, and in some cases, prolonged periods of erectile dysfunction, even after they stop using the medications.

In the study, researchers conducted standardized interviews with 71 men aged 21 to 46 who reported they were in otherwise good health and who claimed they experienced the new onset of sexual side effects after they began finasteride. The study found that "94 percent of the men said they developed low sexual desire, 92 percent said they developed erectile dysfunction, 92 percent said they developed decreased arousal and 69 percent said they developed problems with orgasm. Men in this study reported they used finasteride for an average of 28 months and reported an average duration of persistent sexual side effects for 40 months from the time of stopping finasteride to the interview date."

In short, the connection between pharmaceutical drug treatments and their negative impact on male sex drive has been rather consistent in research trials. It is important that men do not underestimate these risks associated with pharmaceutical treatments for hair loss.

Clearly, this is not a desirable outcome for men, regardless of hair loss or growth. And it is certainly not an outcome that complements the efforts you're making to build an inspiring physique and project an image of enhanced manhood.

An All-Natural Hair-Follicle Support Formulation
Powered by a Clinically Validated DHT Blocker

Now here's the good news! You don't have to live with accelerated hair loss, and you don't have to take pharmaceutical drugs that will sap your libido and sexual vitality. There is an all-natural alternative, scientifically designed and based on emerging new clinical research, that addresses the root cause of male baldness, an over-production of dihydrotestosterone (DHT). Even better, it is further augmented with a number of key biosynergistic active ingredients specifically chosen to further support healthy hair growth while also including a key ingredient that can actually helps ENHANCE male sexual function for a large part of the population. This state-of-the-art, life-enhancing formulation is new from BioQuest and is called FolliGenex.

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Clinical Study Documents
Significant Reductions of Serum DHT

The primary ingredient in FolliGenex, an extract from the berries of the serenoa repens plant, has been the subject of intensive recent investigation on the part of clinical researchers. The liposterolic extract and beta sitosterol found in this ingredient are largely credited for its ability to support healthy hair growth.2

Indeed, one rigorous study undertaken in order to examine the true benefits of this botanical substance with regard to hair health -- a tightly monitored double-blind, placebo-controlled clinical trial examining its efficacy on a population of moderately balding males between 23 and 64 years of age -- supported its activity as a potent 5-alpha-reductase inhibitor and a powerful natural weapon against hair loss. The researchers concluded, "the results of this pilot study showed a highly positive response to treatment."3

In another placebo-controlled study, conducted on a test group of 40 adult men, the key ingredient in FolliGenex reduced serum DHT by 32% in only 6 months, while the placebo group showed no change.4

The proprietary blend in FolliGenex contains the key active ingredient backed by science that inhibits 5-alpha-reductase without sacrificing the integrity of male libido or testosterone levels. Research suggests that the mechanism of this formulation's key ingredient decreases DHT uptake in the hair follicle while also preventing DHT from binding to androgenetic receptors, which in turn helps to prevent the side effects associated with pharmaceutical DHT blocking formulations.  

A Highly Potent Matrix of Support
Factors for Male Function

Even as FolliGenex's main ingredient reduces hair-follicle-destroying DHT, a number of other key botanical extracts are present in perfect proprietary ratio, precision-targeted to deliver powerful support for added hair health benefits. These co-factors have been shown to enhance utilization of nutrients that can help counter age-related hormone imbalances, and even facilitate better sleep.

FolliGenex contains pumpkin seed extract, another potent 5-alpha-reductase inhibitor that has demonstrated synergistic effects with FolliGenex's primary active ingredient.7,8  In addition, quercetin, a bioflavanoid found in red wine, apples, onions and grapefruit, is an antioxidant/anti-inflammatory that has been shown to treat and prevent hair loss.9  Quercetin has also demonstrated significant benefits with regard to male reproductive function (i.e. sperm parameters).10

Also present in FolliGenex, Panax ginseng, one of the most commonly used and researched forms of ginseng, has been shown to help support hair regeneration activity, treating hair loss at the cellular level via proliferation of hair dermal papilla cells.11

Vitamin D, an important fat-soluble vitamin, is complementary to significantly improving sleep quality and overall quality of life.13,14 Zinc, an essential mineral, also has a long documented history of playing a key role in supporting testosterone levels in adult males, a large portion of whom are zinc deficient.15

FolliGenex is unique among hair-growth-support technologies in that it is intended to be taken before bedtime, to support hair follicle health as you sleep. Melatonin, a natural, non-habit forming sleep aid, has been included for its notable effects on improving sleep quality16 as well as its antioxidant and hair growth properties.17-19 In the body, melatonin is a hormone secreted by the pineal gland with many roles, including hair growth.  Research suggests melatonin may be a tolerable alternative to drug treatments for male pattern hair loss.20

Support Hair Growth and Health
to the Fullest with FolliGenex!

Let's face it. The reason we devote so much time and energy in the gym and attention to our diet is because we want to take pride in our appearance and inspire admiration in others when we walk into a room. But what good accrues from all that work, if we wince every time we look in the mirror?

Male pattern baldness atop a perfect physique amounts to an unfinished masterpiece, a flaw that colors our perception of the total image. A full head of hair is the finishing touch, the crowning glory on your work of art.

Growth -- whether it's muscle growth or hair growth -- is inextricably associated with the male essence. With FolliGenex, you can rest assured that you're optimizing healthy hair growth while also supporting a key hormonal mechanism involved in healthy libido, sexual function, and overall male vitality.

The first product of its kind to be designed in strict accordance with groundbreaking published clinical data on its key ingredients, FolliGenex is your first line of defense in preventing thinning hair and a receding hairline, while also providing essential support for healthy male function!

Have you tried one or more pharmaceutical drugs to restore hair health and growth? What have your experiences been with them? Let us know in the comments field below!

References

1 http://www.medicalnewstoday.com/releases/219503.php

2 Murugusundram S. (2009). Serenoa repens: does it have any role in the management of androgenetic alopecia. Journal of Cutaneous and Aesthetic Surgery. 2(1):31-32.

3 http://www.ncbi.nlm.nih.gov/pubmed/12006122

4 http://www.ncbi.nlm.nih.gov/pubmed/11337315

5.Carraro JC, Raynaud JP, Koch G, Chisolm GD, Di Silverio F et al. (1996). Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098. Prostate. 29(4):231-40.

6. Zlotta AR, Teillac P, Raynaud JP, Schulman CC. (2005). Evaluation of male sexual function in patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) treated with a therapeutic agent (Permixon), Tamsulosin or Finasteride. Eur Urol. 48(2):269-76.

7. Gossell-Williams M, Davis A, O'Connor N. (2006). Inhibition of testosterone-induced hyperplasia of the prostate of sprague dawley rats by pumpkin seed oil. J Med Food. 9:284-286.

8. Tsai YS, Tong YC, Cheng JT, Lee CH, Yang FS, Lee HY. (2006). Pumpkin seed oil and phytosterol-F can block testosterone/praszosin-induced prostate growth in rats. Urol Int. 77:269-274.

9. Wikramanayake TC, Villasante AC, Jimenez JJ et al. (2012). Prevention and treatment of alopecia areata with quercetin in the C3H/HeJ mouse model. Cell Stress Chaperones. 17(2):267-274.

10. Khaki A, Fathiazad F, Nouri M, Khaki A, Maleki NA, Khamnei HJ, Ahmad P. (2010). Phytother Res. 24(9):1285-91.

11. Park S, Shin WS, Ho J. (2011). Fructus panax ginseng extract promotes hair regeneration in C57BL/6 mice. J Ethnopharmacol. 138(2):340-4.

12. Fahim MS, Fahim Z, Harman HM, Clevenger TE, Mullins W, Hafez ES. (1982). Effect of Panax ginseng on testosterone levels and prostate in male rats. Arch Adrol. 8(4):261-3.

13. Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B et al. (2011). Effect of vitamin D supplementation on testosterone levels in men.  Horm Metab Res. 43(3):223-5.

14. Huang W, Shah S, Long Q, Crankshaw AK, Tangpricha V. (2013). Improvement of pain, sleep, and quality of life in chronic pain patients with vitamin D supplementation. Clin J Pain. 29(4):341-7.

15. Prasad AS, Mantzoros CS, Beck FW, Hess JW, Brewer GJ. (1996).  Zinc status and serum testosterone levels of healthy adults. Nutrition. 12(5):344-8.

16. Turek FW, Gillette MU. (2004). Melatonin, sleep and circadian rhythms: rationale for development of specific melatonin agonists. Sleep Med. 5(6):523-32.

17. Vural H, Sabancu T, Arslan SO, Aksoy N. (2001). Melatonin inhibits lipid peroxidation and stimulates the antioxidant status of diabetic rats. J Pineal Res. 31(3):193-8.

18. Valcavi R, Zini M, Maestroni GJ, Conti A, Portioli I. (1993). Melatonin stimulates growth hormone secretion through pathways other than the growth hormone-releasing hormone. Clin Endocrinol (Oxf). 39(2):193-9.

19. Valenti S, Giusti M. (2002). Melatonin participates in the control of testosterone secretion from rat testis: an overview of our experience. Ann N Y Acad Sci. 966:284-9.

20. Fischer TW, Trüeb RM et al. (2012). Topical melatonin for treatment of androgenetic alopecia. Int J Trichology. 4(4):238-245.  

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Disclaimer: The articles featured herein are for informational purposes only and should not be construed as medical advice. Specific medical advice should only be obtained from a licensed health care professional. No liability is assumed by ProSource for any information herein.





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